منابع مشابه
Checking in on spindle size
Time keepers abound very cell in the body has its own little clock, according to Emi Nagoshi, Ueli Schibler (University of Geneva, Switzerland), and colleagues. These peripheral clocks may be closely related to the body’s central clock—the suprachiasmatic nucleus (SCN). Neurons of the SCN maintain circadian gene expression for long periods of time. Other cells, however, were thought to rely on ...
متن کاملNew Spin on Spindle Size
JCB • VOLUME 182 • NUMBER 2 • 2008 216 UNTYING TUBE FORMATION From the trachea to the capillaries of the retina, the body teems with tubes. Even the heart is a glorifi ed tube. Two papers have identifi ed a pathway that helps tube cells create an opening. Building a tube from solid tissue involves making space between adjacent cells to form a lumen. The two groups recorded similar results about...
متن کاملChecking cell size in yeast.
To remain viable, cells have to coordinate cell growth with cell division. In yeast, this occurs at two control points: the boundaries between G1 and S phases, also known as Start, and between G2 and M phases. Theoretically, coordination can be achieved by independent regulation of growth and division, or by participation of surveillance mechanisms in which cell size feeds back into cell-cycle ...
متن کاملSamurai Sword Sets Spindle Size
Although the parts list is nearly complete for many cellular structures, mechanisms that control their size remain poorly understood. Loughlin and colleagues now show that phosphorylation of a single residue of katanin, a microtubule-severing protein, largely accounts for the difference in spindle length between two closely related frogs.
متن کاملCytoplasmic volume modulates spindle size during embryogenesis.
Rapid and reductive cell divisions during embryogenesis require that intracellular structures adapt to a wide range of cell sizes. The mitotic spindle presents a central example of this flexibility, scaling with the dimensions of the cell to mediate accurate chromosome segregation. To determine whether spindle size regulation is achieved through a developmental program or is intrinsically speci...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2004
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1676rr5